The aim of the Research Gaps Register is to describe and highlight gaps in primary research identified during evidence synthesis for health policy. The register aims to potentially reduce research waste and increase research efficiency by serving as an evidence-based resource for researchers and research funders, and by shortening the timeline from evidence gap identification to research action.

Each gap serves as a snapshot from the date that evidence synthesis was conducted, and researchers or organisations are encouraged to confirm the currency of identified gaps. The register is updated as new gaps are identified. Researchers and funders are encouraged to consult the register and contact cicer@hiqa.ie for further queries or submissions.

Evidence gap identifierYear identifiedBrief title
ASM12025Clinical and cost-effectiveness of self-management for acute asthma exacerbation
AA12025Clinical and cost effectiveness of anti-interleukin-5 therapy for acute asthma exacerbation
HCAI  32022Effect of single patient room accommodation on healthcare associated infections
UG 12021Standardised and explicit guidance on updating clinical guidelines
EBAR12020Cost of antimicrobial-resistant pathogen outbreaks in public acute hospitals
EBAR22020Association between antimicrobial resistance and intensive care unit admission at patient level
EBAR32020Population-level economic burden of antimicrobial resistant pathogens in acute hospitals
EBAR42020Standardised costing for antimicrobial resistance in acute public hospitals in Ireland
EBAR52020Prescribing practice changes in the general population in response to AMR concern
SCS12019Models of specialist cardiac services networks
SCS22019Impact of changes to specialist cardiac services on clinical decision making, patient outcomes, and healthcare utilisation
SCS32019Percutaneous coronary interventions versus pharmacoinvasive interventions for older adults
SCS42019Minimum volume threshold for percutaneous coronary interventions 
SCS52019Percutaneous coronary intervention volume-outcomes
CODA12019Clinical effectiveness of clinically assisted hydration during end of life care
HCAI 12019Clinical effectiveness of clinically assisted hydration during end-of-life care
HCAI 22019Cost-effectiveness of interventions to improve hand hygiene in high-adherence acute settings
LTH 12019Incidence of intraoperative massive haemorrhage (IMH), and mortality related to IMH, in Ireland
COPD12018Cost-effectiveness of pulmonary rehabilitation for people living with stable chronic obstructive pulmonary disease (COPD)
COPD22018Cost-effectiveness of long-term oxygen therapy (LTOT) for adults living with chronic stable hypoxemia
COPD3 2018Cost-effectiveness of COPD outreach service for adults hospitalised with COPD
NS1 2018Diagnostic accuracy of nutritional screening tools in hospitalised adults
NS22018Accuracy of nutritional screening tools to identify adverse outcomes in hospitalised adults at risk of undernutrition
NS32018Cost-effectiveness of nutritional screening tools in hospitalised adults
INEWS 1 2018Effectiveness of early warning score educational programmes for healthcare workers
INEWS 22018Economic evaluations of acute healthcare early warning systems for adults
INEWS 3 2018Clinical effectiveness of modified acute healthcare early warning systems for older adults living with frailty
INEWS 4 2018Clinical effectiveness of modified acute healthcare early warning systems for adults living with chronic respiratory conditions
INEWS 5 2018Clinical effectiveness of acute healthcare early warning systems for adults (afferent limb)
INEWS 62018Clinical effectiveness of acute healthcare early warning systems for adults (chart design)
INEWS 72018Predictive ability of acute healthcare early warning systems for adults
INEWS 82018Clinical effectiveness of acute healthcare early warning systems for adults (efferent limb (i.e. emergency response systems))
IMEWS1 2017Clinical effectiveness of early warning systems for pregnant and postpartum women during acute maternity care
IMEWS2 2017Development and validation of early warning systems for pregnant and postpartum women during acute maternity care
IMEWS32017Economic evaluation of early warning systems for pregnant women during acute maternity care
SCRIP12017Clinical and cost-effectiveness of risk stratification during the antenatal period
SS12016Clinical effectiveness of smoking cessation interventions in secondary mental health services